SRP8048

PEDF mouse

recombinant, expressed in CHO cells, FLAG^® tagged, >95% (SDS-PAGE)

• 同義詞: Caspin, PC cell-derived growth factor, Pigment epithelium-derived factor, Stromal cell-derived factor 3
• CAS號碼: 607410-75-3
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 生物源: mouse
• 重組細胞: expressed in CHO cells
• 籤條: FLAG^® tagged
• 化驗: >95% (SDS-PAGE)
• 形狀: lyophilized
• 分子量: ~47 kDa by SDS-PAGE
• 包裝: pkg of 10 μg
• 儲存條件: avoid repeated freeze/thaw cycles
• 雜質: <0.01 EU/μg endotoxin, tested
• 顏色: white
• UniProt登錄號: P97298
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: mouse ... Serpinf1(20317)

描述

一般說明

Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

外觀

Lyophilized from PBS.

重構

Reconstitute with 100 μL deionized water.

其他說明

Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG^®-tag.

法律資訊

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable