SRP8035

IL-36α mouse

recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)

• 同義詞: Interleukin-1 family member 6, Interleukin-1 homolog 1, Interleukin-1α, Interleukin-36α
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 生物源: mouse
• 重組細胞: expressed in E. coli
• 共軛: untagged
• 化驗: >95% (SDS-PAGE)
• 形狀: lyophilized
• 分子量: ~17 kDa
• 包裝: pkg of 10 μg
• 雜質: <0.01 EU/μg endotoxin, tested
• UniProt登錄號: Q9JLA2
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: mouse ... Il36a(54448)

描述

一般說明

IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1β, IL-6, TNF-α and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

外觀

Lyophilized from PBS.

重構

Reconstitute with 100 μL deionized water.

其他說明

IL-36alpha (mouse) (aa 8-160) is untagged.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable