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Merck
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重要文件

SRP5131

Sigma-Aldrich

SMAD2, GST tagged human

recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

同義詞:

JV18, JV18-1, MADH2, MADR2, MGC22139, MGC34440, hMAD-2, hSMAD2

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About This Item

CAS號碼:
分類程式碼代碼:
12352200
NACRES:
NA.32
暫時無法取得訂價和供貨情況

生物源

human

重組細胞

expressed in E. coli

化驗

≥70% (SDS-PAGE)

形狀

buffered aqueous glycerol solution

分子量

~90 kDa

NCBI登錄號

應用

cell analysis

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... SMAD2(4087)

外觀

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

準備報告

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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Targeting the transforming growth factor-beta signaling pathway in human cancer.
Nagaraj NS
Expert Opinion on Investigational Drugs (2010)
Signaling of transforming growth factor-beta family members through Smad proteins.
Itoh S
European Journal of Biochemistry (2000)
Alterations in the Smad pathway in human cancers.
Samanta D and Datta PK
Frontiers in Bioscience (Landmark Edition) (2012)
K Eppert et al.
Cell, 86(4), 543-552 (1996-08-23)
The MAD-related (MADR) family of proteins are essential components in the signaling pathways of serine/threonine kinase receptors for the transforming growth factor beta (TGFbeta) superfamily. We demonstrate that MADR2 is specifically regulated by TGFbeta and not bone morphogenetic proteins. The
Alison E John et al.
Methods in molecular biology (Clifton, N.J.), 1627, 351-365 (2017-08-25)
The potent and pluripotent cytokine TGFβ has important roles in normal homeostasis and disease pathogenesis. Once released from cells, TGFβ exists in both latent and functionally active forms. Large amounts of latent TGFβ are secreted from cells and sequestered in

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