推薦產品
生物源
mouse
重組細胞
expressed in E. coli
化驗
≥98% (HPLC)
≥98% (SDS-PAGE)
形狀
lyophilized
效力
5x10^7 units/mg ED50
分子量
21.7 kDa
包裝
pkg of 10 μg
雜質
endotoxin, tested
顏色
white to off-white
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
mouse ... IL6(16193)
相關類別
一般說明
鼠IL-6对人细胞无活性,而人和鼠IL-6对鼠细胞的活性相同。 重组鼠IL-6是含有188个氨基酸残基的21.7 kDa蛋白质。
應用
来自小鼠的IL-6已用于研究IL-6介导的对小鼠前脂肪细胞分化的抑制作用。
生化/生理作用
IL-6是一种多效细胞因子,它能够调节免疫和炎症反应,从而在宿主防御中发挥重要作用。IL-6由T细胞、单核细胞、成纤维细胞、内皮细胞和角质形成细胞产生,具有多种生物学功能。它能刺激B细胞分化和抗体产生,与IL-3协同作用于巨核细胞发育和血小板生成,诱导肝急性期蛋白的表达,并调节骨代谢。IL-6通过IL-6受体系统发出信号,该系统由IL-6R和gp130两条链组成。
外觀
从0.1%TFA中冻干获得
重構
打开样品瓶之前需离心。 在水中重悬至浓度为 0.1-1.0mg/ml。不可涡旋。 该溶液可在2-8°C下储存长达1周。 为了延长储存时间,建议可在含有载体蛋白(如0.1% BSA)的缓冲液中进行进一步的稀释,并分装冻存在-20℃至-80℃下。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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