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重要文件

SRP0474

Sigma-Aldrich

ATAD2A (981-1108) human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

同義詞:

ANCCA, ATPase family, AAA domain containing 2, PRO2000

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.32

生物源

human

重組細胞

expressed in E. coli

化驗

≥90% (SDS-PAGE)

形狀

aqueous solution

分子量

16.2 kDa

包裝

pkg of 100 μg

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... ATAD2(29028)

一般說明

Human Bromodomain ATAD2A (GenBank Accession No. NM_014109) amino acids 981 – 1108 with N-terminal HIS-tag, MW = 16.2 kDa, expressed in an E. coli expression system.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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C Caron et al.
Oncogene, 29(37), 5171-5181 (2010-06-29)
Cancer cells frequently express genes normally active in male germ cells. ATAD2 is one of them encoding a conserved factor harbouring an AAA type ATPase domain and a bromodomain. We show here that ATAD2 is highly expressed in testis as
Ekaterina V Kalashnikova et al.
Cancer research, 70(22), 9402-9412 (2010-09-25)
Chromatin coregulators are important factors in tumorigenesis and cancer progression. ANCCA is an AAA+ ATPase and a bromodomain-containing nuclear coactivator for the estrogen and androgen receptors that is crucial for assembly of chromatin-modifying complexes and proliferation of hormone-responsive cancer cells.

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