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Merck
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重要文件

SRP0428

Sigma-Aldrich

PDE2A active rat

recombinant, expressed in baculovirus infected Sf9 cells, ≥56% (SDS-PAGE)

同義詞:

phosphodiesterase 2A, cGMP-stimulated

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.32
暫時無法取得訂價和供貨情況

生物源

rat

重組細胞

expressed in baculovirus infected Sf9 cells

化驗

≥56% (SDS-PAGE)

形狀

aqueous solution

分子量

133 kDa

包裝

pkg of 5 μg

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

一般說明

Rat PDE2A (GenBank Accession No. NM_00143847) full length with N-terminal His-GST-tag, MW=133 kDa, expressed in a Baculovirus infected Sf9 cell expression system

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Sergio E Martinez et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(20), 13260-13265 (2002-09-25)
Cyclic nucleotide phosphodiesterases (PDEs) regulate all pathways that use cGMP or cAMP as a second messenger. Five of the 11 PDE families have regulatory segments containing GAF domains, 3 of which are known to bind cGMP. In PDE2 binding of
Joachim Seybold et al.
Blood, 105(9), 3569-3576 (2005-01-15)
The pleiotropic cytokine tumor necrosis factor-alpha (TNF-alpha) and thrombin lead to increased endothelial permeability in sepsis. Numerous studies demonstrated the significance of intracellular cyclic nucleotides for the maintenance of endothelial barrier function. Actions of cyclic adenosine monophosphate (cAMP) and cyclic

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