跳轉至內容
Merck
全部照片(2)

文件

SRP0424

Sigma-Aldrich

Tankyrase 2 [849-1166] active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥30% (SDS-PAGE)

同義詞:

PARP5b, PARP5c, TNKS2, Tankyrase 2, poly(ADP-ribosyl)transferase 5b

登入查看組織和合約定價


About This Item

分類程式碼代碼:
12352200
NACRES:
NA.32

生物源

human

重組細胞

expressed in baculovirus infected Sf9 cells

化驗

≥30% (SDS-PAGE)

形狀

aqueous solution

分子量

62 kDa

包裝

pkg of 10 μg

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... TNKS2(80351)

一般說明

TNKS2 (TRF1-interacting ankyrin-related ADP-ribose polymerase 2), also known as PARP5B, tanykyrase-2, or TNKL (GenBank Accession No. NM_025235) amino acids 849-1166 (end) with N-terminal GST-tag, MW=62kDa, expressed in Sf9 cells via a Baculovirus expression system.

應用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

外觀

Formulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 Mm KCl, 4 mM glutathione, 20% glycerol, and 3 mM DTT.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

P G Kaminker et al.
The Journal of biological chemistry, 276(38), 35891-35899 (2001-07-17)
Tankyrase (TANK1) is a human telomere-associated poly(ADP-ribose) polymerase (PARP) that binds the telomere-binding protein TRF1 and increases telomere length when overexpressed. Here we report characterization of a second human tankyrase, tankyrase 2 (TANK2), which can also interact with TRF1 but
Natalie Sidorova et al.
Cell and tissue research, 323(1), 137-145 (2005-09-10)
Tankyrase, which functions at telomeres and other cellular compartments, is thought to be a positive regulator of telomerase; its isoenzyme tankyrase 2 has been cloned as a putative cancer antigen. This pilot immunohistochemical study was designed to examine whether tumors

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務