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Merck
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SML3573

Sigma-Aldrich

Goitrin

≥98% (HPLC)

同義詞:

(-)-5-Vinyl-2-oxazolidinethione, (5S)-5-Ethenyl-1,3-oxazolidine-2-thione, L-Goitrin

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About This Item

經驗公式(希爾表示法):
C5H7NOS
CAS號碼:
分子量::
129.18
MDL號碼:
分類程式碼代碼:
51111800
分類程式碼代碼:
12352200
NACRES:
NA.21

品質等級

化驗

≥98% (HPLC)

形狀

powder

光學活性

[α]/D 85 to 67° (C=1.0g/100mL, CDCl3 )

顏色

white to beige

溶解度

DMSO: 2 mg/mL, clear

儲存溫度

2-8°C

SMILES 字串

S=C1NC[C@H](C=C)O1

生化/生理作用

Goitrin is a sulfur containing alkaloid isolated from Isatis indigotica (Ban Lan Gen) and Brassica vegetables (yellow turnip, broccoli) that exhibits antiviral, anticancer, and antithyroid activities. Epigoitrin and goitrin appear to show virucidal effect on influenza virus A (H1N1) in vitro and in ovo.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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1-5-Vinyl-2-thiooxazolidone, an antithyroid compound from yellow turnip and from Brassica seeds
The Journal of Biological Chemistry, 181(1), 121-130 (1941)
Stereospecific Assay of (R)- and (S)-Goitrin in Commercial Formulation of Radix Isatidis by Reversed Phase High-Performance Liquid Chromatography
Lixing Nie, Zhong Dai, Shuangcheng Ma
Journal of Analytical Methods in Chemistry, 2017, 2810565-2810565 (2017)
Antiviral activity of Isatidis Radix derived glucosinolate isomers and their breakdown products against influenza A in vitro/ovo and mechanism of action
Li-Xing Nie
Journal of Ethnopharmacology, 251, 112550-112550 (2020)

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