SML3429

Maropitant

≥98% (HPLC)

• 同義詞: (2S,3S)-2-Benzhydryl-N-[(5-tert-butyl-2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine, (2S,3S)-N-(5-tert-Butyl-2-methoxyphenyl)methyl-2-diphenylmethyl-1-azabicyclo[2.2.2]octan-3-amine, 2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(5-tert-butyl-2-methoxybenzyl)amine, CJ-11,972, CJ-11972
• 經驗公式（希爾表示法）: C₃₂H₄₀N₂O
• CAS號碼: 147116-67-4
• 分子量：: 468.67
• MDL號碼: MFCD25541735
• 分類程式碼代碼: 51111800
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear (Warmed)
• 儲存溫度: -10 to -25°C
• SMILES 字串: N21[C@H]([C@H](C(CC2)CC1)NCc5c(ccc(c5)C(C)(C)C)OC)C(c4ccccc4)c3ccccc3
• InChI: 1S/C32H40N2O/c1-32(2,3)27-15-16-28(35-4)26(21-27)22-33-30-25-17-19-34(20-18-25)31(30)29(23-11-7-5-8-12-23)24-13-9-6-10-14-24/h5-16,21,25,29-31,33H,17-20,22H2,1-4H3/t30-,31-/m0/s1
• InChI 密鑰: OMPCVMLFFSQFIX-CONSDPRKSA-N

描述

生化／生理作用

Maropitant is a neurokinin-1 receptor (NK-1R) antagonist with in vivo antiemetic efficacy.

Neurokinin-1 receptor (NK-1R) antagonist with in vivo antiemetic efficacy.

安全資訊

• 象形圖: GHS08,GHS07,GHS09
• 訊號詞: Warning
• 危險聲明: H317,H373,H410
• 防範說明: P260 - P272 - P273 - P280 - P302 + P352 - P314
• 危險分類: Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1 - STOT RE 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable