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Merck
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重要文件

SML3080

Sigma-Aldrich

C14PC

≥98% (HPLC)

同義詞:

2-[[Hydroxy(tetradecyloxy)phosphinyl]oxy]-N,N,N-trimethyl- ethanaminium inner salt, CDI 166493, D 19390, FOS 14, Fos-choline 14, Tetradecylphosphocholine, n-Tetradecyl-phosphocholine, n-Tetradecylphosphocholine

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About This Item

經驗公式(希爾表示法):
C19H42NO4P
CAS號碼:
分子量::
379.51
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77
暫時無法取得訂價和供貨情況

品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 2 mg/mL, clear

儲存溫度

−20°C

SMILES 字串

[O-]P(OCCCCCCCCCCCCCC)(OCC[N+](C)(C)C)=O

InChI

1S/C19H42NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-18-23-25(21,22)24-19-17-20(2,3)4/h5-19H2,1-4H3

InChI 密鑰

BETUMLXGYDBOLV-UHFFFAOYSA-N

生化/生理作用

inhibitor of MARSA virulence
n-Tetradecylphosphocholine (C14PC), a more stable analog of myristoyl lysophosphatidylcholine, is an inhibitor of MARSA virulence. C14PC is a broad-spectrum inhibitor of Panton–Valentine leucocidin (PVL), LukED and α−toxin. C14PC protects primary human immune cells in vitro against cytolysis by PVL and α-toxin. C14PC can be used as a detergent for membrane solubilization.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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Jie Liu et al.
The Journal of biological chemistry, 295(18), 5944-5959 (2020-03-18)
The rapid emergence and dissemination of methicillin-resistant Staphylococcus aureus (MRSA) strains poses a major threat to public health. MRSA possesses an arsenal of secreted host-damaging virulence factors that mediate pathogenicity and blunt immune defenses. Panton-Valentine leukocidin (PVL) and α-toxin are
Danyang Guo et al.
Metabolism: clinical and experimental, 107, 154232-154232 (2020-04-18)
Parasympathetic nerve (PN) signaling plays a crucial role in the maintenance of pancreatic β-cell volume density (Vβ). PN may be pathologically affected in diabetic polyneuropathy (DPN). However, the association between the reduction of PNs in islets and Vβ and the

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