SML3025

BAY-784

≥98% (HPLC)

• 同義詞: BAY-784, (2S)-N-[[3-Chloro-5-(trifluoromethyl)-2-pyridyl]methyl]-2-cyclopropyl-1-(4-fluorophenyl)sulfonyl-1′,1′-dioxo-spiro[indoline-3,4′-thiane]-5-carboxamide, (2S)-N-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]-2-cyclopropyl-1-[(4-fluorophenyl)sulfonyl]-1,2,2?,3?,5?,6?-hexahydro-spiro[3H-indole-3,4?-[4H]thiopyran]-5-carboxamide 1?,1?-dioxide, BAY 1214784, BAY-1214784
• 經驗公式（希爾表示法）: C₂₉H₂₆ClF₄N₃O₅S₂
• CAS號碼: 1631164-24-3
• 分子量：: 672.11
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 光學活性: [α]/D -120 to -100°, c = 0.5 in chloroform-d
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: O=S(CCC1(C2=C(N3S(C4=CC=C(F)C=C4)(=O)=O)C=CC(C(NCC5=C(Cl)C=C(C(F)(F)F)C=N5)=O)=C2)[C@@H]3C6CC6)(CC1)=O

描述

生化／生理作用

BAY-784 is an orally available, non-toxic, potent, and selective antagonist of human Gonadotropin-Releasing Hormone Receptor [hGnRH-R], which is potently active in other species including rate, dogs and cynomolgus monkey. It partially lowered plasma luteinizing hormone levels in humans. BAY-784 exhibits favorable drug metabolism and pharmacokinetic (DMPK) profile thus is suitable for in vivo studies.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable