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Merck
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重要文件

SML1756

Sigma-Aldrich

BAY-299

≥98% (HPLC)

同義詞:

6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione

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About This Item

經驗公式(希爾表示法):
C25H23N3O4
分子量::
429.47
分類程式碼代碼:
12352200
暫時無法取得訂價和供貨情況

品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 20 mg/mL, clear

儲存溫度

2-8°C

生化/生理作用

BAY-299 is a potent and selective inhibitor of BRD1 and the second bromodomain of TAF1 (Transcription initiation factor TFIID subunits 1). BAY-299 is selective over other bromodomains including the other members of the BRPF family, and BRD9, ATAD2 and BRD4. BAY-364 is structurally similar to BAY-299 and serves as inactive control. For full characterization details, please visit the BAY-299 probe summary on the Structural Genomics Consortium (SGC) website.

BAY-364 (BAY-299N) is the negative control for the active, structurally similar probe, BAY-299. BAY-364 is available from Sigma. To learn more about and purchase BAY-364, click here.

To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
BAY-299 is a potent and selective inhibitor of BRD1 and the second bromodomain of TAF1.

特點和優勢

BAY-299 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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文章

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

我們提供各種小分子研究工具,例如轉錄因子調節劑、染色質修飾酵素的抑制劑,以及用於基因調控研究中靶點鑑定和驗證的激效劑/拮抗劑;以下是這些研究工具的精選。

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我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

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