SML1487

ABT-089 dihydrochloride

≥98% (HPLC)

• 同義詞: 2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride, Pozanicline dihydrochloride
• 經驗公式（希爾表示法）: C₁₁H₁₆N₂O · 2HCl
• CAS號碼: 161416-61-1
• 分子量：: 265.18
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825916
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 光學活性: [α]/D +20 to +30°, c = 1 in methanol
• 顏色: white to beige
• 溶解度: H₂O: 20 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: CC1=C(OC[C@@H]2CCCN2)C=CC=N1.[H]Cl.[H]Cl
• InChI: 1S/C11H16N2O.2ClH/c1-9-11(5-3-6-12-9)14-8-10-4-2-7-13-10;;/h3,5-6,10,13H,2,4,7-8H2,1H3;2*1H/t10-;;/m0../s1
• InChI 密鑰: UGVSESCRKJTJAK-XRIOVQLTSA-N

描述

生化／生理作用

ABT-089 (Pozanicline) is a subtype-selective neuronal nicotinic receptor partial agonist binding primarily to the α4β2 and also α6β2 subtypes. It has been investigated for alleviating symptoms of nicotine withdrawal including cognitive deficits and anxiety.

ABT-089 is a subtype-selective neuronal nicotinic receptor partial agonist binding primarily to the α4β2 and also α6β2 subtypes.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P264 - P270 - P301 + P312 - P501
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable