SML0803

VUF10661

≥98% (HPLC), Chemokine receptor CXCR3 agonist, powder

• 同義詞: (3S)-N-[(1S)-5-Amino-1-[[(2,2-diphenylethyl)amino]carbonyl]pentyl]-2-(1,4-dioxo-4-phenylbutyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
• 經驗公式（希爾表示法）: C₄₀H₄₄N₄O₄
• CAS 編號: 914291-63-7
• 分子量：: 644.80
• UNSPSC Code: 51111800
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

屬性

• 產品名稱: VUF10661, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: −20°C

描述

Biochem/physiol Actions

VUF10661 is a potent agonist of the chemokine receptor CXCR3.

VUF10661 is a potent agonist of the chemokine receptor CXCR3. VUF10661 induces receptor internalization, recruitment of ?-arrestins and activates Gi proteins with similar potency to endogenous CXCL ligands.

Features and Benefits

This compound is featured on the Chemokine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全資訊

• 圖示: GHS06
• 警示詞: Danger
• 危險代碼: H301,H315,H319,H335,H413
• 預防性聲明: P273 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 靶向器官: Respiratory system
• 存儲類別/等級: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 到底發生了什麼事？: WGK 3
• 閃點 (F): Not applicable
• 閃點（°C）: Not applicable