The stability of this material in solution at 4°C has not been determined. Following reconstitution, aliquot and freeze at -20°C for up to 3 months.
推薦產品
化驗
≥98% (HPLC)
形狀
powder
顏色
white to light brown
溶解度
DMSO: 10 mg/mL, clear
儲存溫度
2-8°C
SMILES 字串
[s]1c2c(c(c1NC(=S)NC(=O)c3ccccc3)C(=O)O)CC(OC2)(C)C
InChI
1S/C18H18N2O4S2/c1-18(2)8-11-12(9-24-18)26-15(13(11)16(22)23)20-17(25)19-14(21)10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3,(H,22,23)(H2,19,20,21,25)
InChI 密鑰
ATSWBWHRHAQVFM-UHFFFAOYSA-N
生化/生理作用
CID 1067700可拮抗ras相关蛋白Rab-7,并减少B细胞中的类开关DNA重组(CSR)以及浆细胞的存活。[1]
CID 1067700是Ras相关GTPase的一种有效的竞争性抑制剂。
CID 1067700是Ras相关GTPase的一种有效的竞争性抑制剂,可与Rab7核苷酸结合位点发生有效的结合。
特點和優勢
这种化合物是环核苷酸研究的特色产品。点击此处发现更多特色环核苷酸产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
從最近期的版本中選擇一個:
分析證明 (COA)
Lot/Batch Number
A Remedy for Lupus through Restraining Rab7
How H I V.
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Experimental cell research, 370(1), 87-97 (2018-06-17)
Autophagy dysfunction has been observed in intervertebral disc degeneration (IVDD) cells, a main contributing factor to cell death, but the precise role of autophagy during IVDD is still controversial. This study aimed to investigate the role of autophagy involved in
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Lin Bai et al.
Cell death & disease, 12(4), 392-392 (2021-04-14)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease caused by motoneuron loss, for which there is currently no effective treatment. Statins, as inhibitors of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase, are used as drugs for treatment for a variety of disease such
Yong Lin et al.
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Glucosamine (GlcN), a dietary supplement widely utilized to promote joint health and effective in the treatment of osteoarthritis, is an effective macroautophagy/autophagy activator in vitro and in vivo. Previous studies have shown that autophagy is required for hepatitis B virus
文章
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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After resuspending 5 mg CID 1067700 in DMSO, should it still be stored at 4°C or should it be stored at -20°C?
1 answer-
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