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Merck
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重要文件

SML0545

Sigma-Aldrich

CID 1067700

≥98% (HPLC)

同義詞:

2-(苯甲酰氨基甲硫酰基氨基)-5,5-二甲基-4,7-二氢噻吩并[2,3-c]吡喃-3-羧酸, 2-[[(苯甲酰基氨基)硫代甲酰]氨基]-4,7-二氢-5,5-二甲基-5H-噻吩并[2,3-C]吡喃-3-羧酸, CID-1067700, CID1067700, SID57578339

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About This Item

經驗公式(希爾表示法):
C18H18N2O4S2
CAS號碼:
分子量::
390.48
分類程式碼代碼:
12352200
NACRES:
NA.77
暫時無法取得訂價和供貨情況

化驗

≥98% (HPLC)

形狀

powder

顏色

white to light brown

溶解度

DMSO: 10 mg/mL, clear

儲存溫度

2-8°C

SMILES 字串

[s]1c2c(c(c1NC(=S)NC(=O)c3ccccc3)C(=O)O)CC(OC2)(C)C

InChI

1S/C18H18N2O4S2/c1-18(2)8-11-12(9-24-18)26-15(13(11)16(22)23)20-17(25)19-14(21)10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3,(H,22,23)(H2,19,20,21,25)

InChI 密鑰

ATSWBWHRHAQVFM-UHFFFAOYSA-N

生化/生理作用

CID 1067700可拮抗ras相关蛋白Rab-7,并减少B细胞中的类开关DNA重组(CSR)以及浆细胞的存活。[1]
CID 1067700是Ras相关GTPase的一种有效的竞争性抑制剂。
CID 1067700是Ras相关GTPase的一种有效的竞争性抑制剂,可与Rab7核苷酸结合位点发生有效的结合。

特點和優勢

这种化合物是环核苷酸研究的特色产品。点击此处发现更多特色环核苷酸产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease caused by motoneuron loss, for which there is currently no effective treatment. Statins, as inhibitors of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase, are used as drugs for treatment for a variety of disease such
Yong Lin et al.
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Glucosamine (GlcN), a dietary supplement widely utilized to promote joint health and effective in the treatment of osteoarthritis, is an effective macroautophagy/autophagy activator in vitro and in vivo. Previous studies have shown that autophagy is required for hepatitis B virus

文章

Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.

Questions

  1. After resuspending 5 mg CID 1067700 in DMSO, should it still be stored at 4°C or should it be stored at -20°C?

    1 answer
    1. The stability of this material in solution at 4°C has not been determined. Following reconstitution, aliquot and freeze at -20°C for up to 3 months.

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