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Merck
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重要文件

SML0512

Sigma-Aldrich

BLT-4

≥98% (HPLC)

同義詞:

INF 271, MIT 9952-29, N-(2-Methoxyphenyl)-N′-2-naphthalenyl-urea

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About This Item

經驗公式(希爾表示法):
C18H16N2O2
CAS號碼:
分子量::
292.33
MDL號碼:
分類程式碼代碼:
51111800
PubChem物質ID:
NACRES:
NA.77
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品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 15 mg/mL (clear solution)

儲存溫度

room temp

SMILES 字串

COc1ccccc1NC(=O)Nc2ccc3ccccc3c2

InChI

1S/C18H16N2O2/c1-22-17-9-5-4-8-16(17)20-18(21)19-15-11-10-13-6-2-3-7-14(13)12-15/h2-12H,1H3,(H2,19,20,21)

InChI 密鑰

ISADADAHPHHLEM-UHFFFAOYSA-N

相關類別

生化/生理作用

BLT-4 is a SR-BI (Scavenger receptor, class B, type I) inhibitor.
BLT-4 is a blocker of lipid transport-4 (BLT-4). BLT-4 is a specific, reversible inhibitor of scavenger receptor, class B, type I (SR-BI) mediated lipid transfer. The molecule blocks the cellular uptake and transfer of cholesterol ester from HDL.

象形圖

Environment

訊號詞

Warning

危險聲明

防範說明

危險分類

Aquatic Acute 1 - Aquatic Chronic 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Thomas J F Nieland et al.
Journal of lipid research, 45(7), 1256-1265 (2004-04-23)
Scavenger receptor class B type I (SR-BI) and ABCA1 are structurally dissimilar cell surface proteins that play key roles in HDL metabolism. SR-BI is a receptor that binds HDL with high affinity and mediates both the selective lipid uptake of
Elsa Westerlund et al.
Frontiers in immunology, 10, 1385-1385 (2019-07-06)
The common human pathogen Group A Streptococcus (GAS) causes superficial as well as invasive, life-threatening diseases. An increase in the occurrence of invasive GAS infection by strains of the M1 and M89 serotypes has been correlated with increased expression of
Guillemette Maurin et al.
AIDS (London, England), 29(9), 1025-1033 (2015-07-01)
Chronic hepatitis C virus (HCV) infection causes severe liver disease in HIV-infected patients and liver transplant recipients. The impact of serum and immunoglobulin on viral entry was analysed in these patients. Sera from 60 anti-HCV positive patients, including 30 who

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