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SML0175

Sigma-Aldrich

Pyrovalerone hydrochloride

≥98% (HPLC)

同義詞:

1-(4-Methylphenyl)-2-(1-pyrrolidinyl)-1-pentanone hydrochloride, Centroton, F 1983, Sp 1059, Thymergix

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About This Item

經驗公式(希爾表示法):
C16H23NO·HCl
CAS號碼:
分子量::
281.82
EC號碼:
分類程式碼代碼:
41116107
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

drug control

psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

顏色

off-white to light brown

溶解度

H2O: ≥5 mg/mL at 60 °C

儲存溫度

2-8°C

InChI

1S/C16H23NO.ClH/c1-3-6-15(17-11-4-5-12-17)16(18)14-9-7-13(2)8-10-14;/h7-10,15H,3-6,11-12H2,1-2H3;1H

InChI 密鑰

MWRACNBZNVAJHE-UHFFFAOYSA-N

應用

Pyrovalerone hydrochloride may be used in dopamine-mediated cell signaling studies.

生化/生理作用

Pyrovalerone hydrochloride is a rapidly-absorbed psychostimulant. It belongs to the class of synthetic cathinones often used as performance-enhancing agent by athletes before being banned.
Pyrovalerone is a norepinephrine-dopamine reuptake inhibitor (NDRI) that acts as a CNS stimulant.

特點和優勢

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Jane M Prosser et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 8(1), 33-42 (2011-11-24)
Synthetic cathinones have recently emerged and grown to be popular drugs of abuse. Their dramatic increase has resulted in part from sensationalized media attention as well as widespread availability on the Internet. They are often considered "legal highs" and sold
H S Shin et al.
Journal of analytical toxicology, 20(7), 568-572 (1996-11-01)
Detection and identification of pyrovalerone and its metabolite, a hydroxylated product, are described. Their identities were confirmed by comparing their mass spectra and gas chromatographic retention times with those of the synthetic standards. The analytical method of pyrovalerone and its
C Héron et al.
European journal of pharmacology, 264(3), 391-398 (1994-11-03)
We have studied the ability of various uptake blockers to protect the dopamine neuronal carrier labeled with [3H]GBR 12783 (1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-2-(propenyl)-piperazine) against N-ethylmaleimide-induced alkylation, using membrane preparations obtained from rat striatum. Pure uptake inhibitors such as mazindol, pyrovalerone, nomifensine and methylphenidate
Mark Durham
Emergency medicine journal : EMJ, 28(12), 1059-1060 (2011-03-17)
Since the classification of miaow miaow (mephedrone) as a class B drug in April this year, a new drug is emerging as a so-called 'legal high'. Deaths have already been attributed to ivory wave in different parts of the country.
The metabolism of pyrovalerone hydrochloride.
W Michaelis et al.
Journal of medicinal chemistry, 13(3), 497-503 (1970-05-01)

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