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重要文件

SML0054

Sigma-Aldrich

五味子醇甲

≥98% (HPLC)

同義詞:

(+)-五味子乙素, 五味子碱, 五味子素, 五味子醇 A, 五味子醇甲

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About This Item

經驗公式(希爾表示法):
C24H32O7
CAS號碼:
分子量::
432.51
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
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化驗

≥98% (HPLC)

形狀

powder

光學活性

[α]/D 75 to 95°, c = 1 in methanol

顏色

white to beige

溶解度

DMSO: ≥13 mg/mL

儲存溫度

room temp

SMILES 字串

COc1cc2C[C@H](C)[C@@](C)(O)Cc3cc(OC)c(OC)c(OC)c3-c2c(OC)c1OC

InChI

1S/C24H32O7/c1-13-9-14-10-16(26-3)20(28-5)22(30-7)18(14)19-15(12-24(13,2)25)11-17(27-4)21(29-6)23(19)31-8/h10-11,13,25H,9,12H2,1-8H3/t13-,24-/m0/s1

InChI 密鑰

YEFOAORQXAOVJQ-RZFZLAGVSA-N

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相關類別

應用

五味子甲素可用于氧化应激相关的细胞信号传导研究。

生化/生理作用

五味子甲素是一种天然产物,具有抗氧化和抗炎作用。减少 ROS 的形成,抑制线粒体途径的凋亡过程和氧化应激。据报道,五味子甲素具有保肝、抗肿瘤、抗病毒、抗遗忘作用,对谷氨酸引起的神经毒性具有神经保护活性。
抗氧化剂;抗炎,减少氧化应激。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Chun-hui Ma et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(30), 3444-3451 (2011-10-04)
In this study, ester-bond biphenyl cyclooctene lignans were efficiently hydrolytically degraded into free biphenyl cyclooctene lignans by ion exchange resin transformation and simultaneous removal of impurities by macroporous resin. The OH-type strongly basic anion exchange resin 201×7 was the best
Elina Hakala et al.
The Journal of antibiotics, 68(10), 609-614 (2015-05-07)
Lignans from Schisandra chinensis berries show various pharmacological activities, of which their antioxidative and cytoprotective properties are among the most studied ones. Here, the first report on antibacterial properties of six dibenzocyclooctadiene lignans found in Schisandra spp. is presented. The
Jiaming Yang et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(11), 998-1005 (2011-04-26)
This study examined the effect of schisandrin, one of the major lignans isolated from Schisandra chinensis, on spontaneous contraction in rat colon and its possible mechanisms. Schisandrin produced a concentration-dependent inhibition (EC₅₀=1.66 μM) on the colonic spontaneous contraction. The relaxant
Di Hu et al.
Oxidative medicine and cellular longevity, 2012, 721721-721721 (2012-07-26)
In the present study, we examined the effect of schisandrin (SCH) of Schisandra chinensis on the amyloid-beta(1-42)- (Aβ(1-42)-) induced memory impairment in mice and elucidated the possible antioxidative mechanism. Mice were intracerebroventricular (i.c.v.) injected with the aggregated Aβ(1-42) and then
Chun-hui Ma et al.
Analytica chimica acta, 689(1), 110-116 (2011-02-23)
The ionic liquid-based ultrasonic-assisted extraction (ILUAE) has been successfully applied in extracting four biphenyl cyclooctene lignans from the fruit of Schisandra chinensis Baill. Seventeen different types of ionic liquids with different cations and anions have been investigated. 0.8 M 1-lauryl-3-methylimidazolium

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