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SML0014

Sigma-Aldrich

Scutellarin hydrate

≥98% (HPLC)

同義詞:

5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-ß-D-glucopyranosiduronic acid hydrate, 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one hydrate, Breviscapin, Scutellarein-7-O-β-D-glucuronide

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About This Item

經驗公式(希爾表示法):
C21H18O12 · xH2O
CAS號碼:
分子量::
462.36 (anhydrous basis)
分類程式碼代碼:
12352200
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

儲存條件

desiccated

顏色

yellow

溶解度

DMSO: ≥10 mg/mL

儲存溫度

2-8°C

應用

Scutellarin hydrate may be used in MAPK-mediated cell signaling studies.

生化/生理作用

Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.

特點和優勢

This compound is featured on the MAPKs and Nitric Oxide Synthases pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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文章

We offer many products related to nitric oxide synthases for your research needs.

我們提供許多與一氧化氮合酶相關的產品,以滿足您的研究需求。

有絲分裂原活化蛋白激酶 (MAPK) 家族由壓力活化 (SAPK) 和 MAPKs 組成。瞭解它們對各種刺激介導細胞反應的信號轉導級聯網。

The mitogen-activated protein kinase (MAPK) family consists of stress-activated (SAPK) and MAPKs. Learn about their network of signal transduction cascades that mediate cellular responses to a diverse range of stimuli.

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

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