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重要文件

SMB00378

Sigma-Aldrich

二烯丙基二硫

≥98% (HPLC)

同義詞:

烯丙基二硫醚, 二烯丙基二硫

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About This Item

線性公式:
CH2=CHCH2SSCH2CH=CH2
CAS號碼:
分子量::
146.27
Beilstein:
1699241
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.25
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生物源

Allium sativum L.

品質等級

蒸汽密度

>5 (vs air)

蒸汽壓力

1 mmHg ( 20 °C)

化驗

≥98% (HPLC)

形狀

oil

顏色

colorless to yellow

折射率

n20/D 1.541 (lit.)

bp

180-195 °C (lit.)

密度

1.008 g/mL at 25 °C (lit.)

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

−20°C

SMILES 字串

C=CCSSCC=C

InChI

1S/C6H10S2/c1-3-5-7-8-6-4-2/h3-4H,1-2,5-6H2

InChI 密鑰

PFRGXCVKLLPLIP-UHFFFAOYSA-N

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一般說明

二烯丙基二硫(DADS)是一种油溶性挥发性有机硫化物,天然存在于大蒜(Allium sativum)中。[1][2]化学结构简单,由两个硫原子与两个烯丙基连接而成。[2]该成分是大蒜辣味的来源。[3]

應用

二烯丙基二硫已用于:
  • 研究其对不同神经胶质瘤细胞系凋亡诱导和细胞活力的影响[4]
  • 作为处理试剂和阳性对照,评估核因子E2相关因子(Nrf2)对乳腺癌细胞的抗炎调节作用[5]
  • 作为可用底物,检测乙酸铅/硫化铅方法的硫化氢(H2S)生成[1]

生化/生理作用

二烯丙基二硫是一种强效抗癌剂。[6]可减少致癌物诱导癌症,在体内和体外模型中均具有抗增殖活性。[6]二烯丙基二硫(DADS)可增强绿茶对高脂高糖(HF/HS)喂养小鼠的抗肥胖和抗炎活性。[7]还具有抗氧化、抗微生物、心血管保护和神经保护活性。[2]二烯丙基二硫(DADS)具有抗有丝分裂和抗肿瘤作用,可抑制体内结肠肿瘤性病变的有丝分裂和体外实验中结肠肿瘤细胞生长。[8]
天然存在于大蒜中的有机硫化合物。使蒜泥发出刺鼻的气味。抗癌药物,并可能提供对心血管疾病的保护。

象形圖

Skull and crossbones

訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

143.6 °F - closed cup

閃點(°C)

62 °C - closed cup


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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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