The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 124-223 of human IL1 beta (NP_000567.1).
外觀
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
儲存和穩定性
Store at -20℃. Avoid freeze / thaw cycles.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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分析證明 (COA)
Lot/Batch Number
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