The specific epitope sequence is not available. This gene is mapped to human chromosome 11q23.2–11q23.3. The immunogen is a phospho-peptide corresponding to Phospho-Histone H2AX (Ser139).
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重組細胞
expressed in HEK 293 cells
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
RM224, monoclonal
recombinant monoclonal
形狀
buffered aqueous glycerol solution
物種活性
human
濃度
~1 mg/mL
技術
ELISA: 0.2- 1 μg/mL
immunoblotting: 0.5-2 μg/mL
immunocytochemistry: 0.5-2 μg/mL
同型
IgG
NCBI登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
phosphorylation (pSer139)
基因資訊
human ... H2AX(3014)
一般說明
Histone H2AX (H2A histone family member X), a histone variant present in almost all eukaryotes, is coded by H2AFX gene. It is mapped to human chromosome 11q23.2–11q23.3.
特異性
This antibody reacts to Histone H2A.X only when phosphorylated at serine 139. No cross reactivity with other phosphorylated histones.
免疫原
Synthetic peptide corresponding to Phospho-Histone H2AX (Ser139)
生化／生理作用
H2AX (H2A histone family member X) helps to maintain genome stability. It plays an important role in localisation and structuring of the repair focus. H2AX also plays an active role in supplying the active repair proteins. γH2AX participates in DSB repair. This protein serves as a signal and target of phosphorylation in the spreading phase.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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I pretend to use this antibody with another organism, so I need to know the inmunogenic sequence or epitope.
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