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SAB4503371

Sigma-Aldrich

Anti-NT5C1A antibody produced in rabbit

affinity isolated antibody

同義詞:

Cytosolic 5′-nucleotidase 1A, Cytosolic 5′-nucleotidase IA, cN-I, cN-IA, cN1A

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 41 kDa

物種活性

mouse, human

濃度

~1 mg/mL

技術

ELISA: 1:20000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000

NCBI登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... 5NT1A(84618)

一般說明

Anti-NT5C1A Antibody detects endogenous levels of total NT5C1A protein. The NT5C1A (5′-nucleotidase, cytosolic IA) gene is mapped to human chromosome 1p34. The protein encoded is ubiquitously expressed and is localized to the cytoplasm.

免疫原

The antiserum was produced against synthesized peptide derived from human NT5C1A.

Immunogen Range: 151-200

生化/生理作用

NT5C1A (5′-nucleotidase, cytosolic IA) forms a tetramer with AMP (adenosine monophosphate) and serves as a primary substrate in adenosine pathway to control the level of metabolite produced. NT5C1A catalyzes the dephosphorylation of AMP to adenosine.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Pharmacogenetic characterization of naturally occurring germline NT5C1A variants to chemotherapeutic nucleoside analogs.
Saliba J, et al.
Pharmacogenetics and Genomics, 26(6), 271-271 (2016)
Suppression of 5'nucleotidase enzymes promotes AMPK phosphorylation and metabolism in human and mouse skeletal muscle.
Kulkarni S S, et al.
The Journal of Biological Chemistry (2011)
Expression of cytosolic 5? nucleotidase does not correlate with expression of oxidative metabolism marker: myoglobine in human skeletal muscles.
Lechward K and Tkacz-Stachowska K
Acta biochimica et biophysica Sinica, 41(4), 280-284 (2009)

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