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SAB4502905

Sigma-Aldrich

Anti-Synapsin, N-Terminal antibody produced in rabbit

affinity isolated antibody

同義詞:

Brain protein 4.1, SYN-1, synapsin I

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 74 kDa

物種活性

mouse, rat, human

濃度

~1 mg/mL

技術

ELISA: 1:20000
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... SYN1(6853)

相關類別

一般說明

Anti-Synapsin Antibody detects endogenous levels of total Synapsin protein.
Synapsin I (SYN1) is a synaptic vesicle associated protein. It is present in the central nervous system like olfactory bulb, cerebral cortex, hippocampus, basal ganglia, thalamus, hypothalamus, cerebellum, pons-medulla, spinal cord and posterior pituitary gland. The protein is found in the nucleus and cytoplasm of granule cells, and in the glomerular synaptic complex of the cerebellum. SYN1 gene is located in human chromosome Xp11.3.

免疫原

The antiserum was produced against synthesized peptide derived from human Synapsin.

Immunogen Range: 3-52

應用

Anti-Synapsin, N-Terminal antibody has been used in immunohistochemistry.

生化/生理作用

Synapsin I (SYN1) plays an important role in neurotransmitter release, exocytosis of the synaptic vesicles, neurite elongation and synaptogenesis. Brain dysfunction occurs due to improper expression of synapsin I.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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A novel method to derive and expand mice neural stem cells efficiently without neuro-sphere formation.
Ma ZZ, et al.
International Journal of Clinical and Experimental Medicine, 8(8), 12834?12841-12834?12841 (2015)
Evidence for a Turner syndrome locus or loci at Xp11. 2-p22. 1.
Zinn AR, et al.
American Journal of Human Genetics, 63(6), 1757-1766 (1998)
Increased synapsin I expression in cerebral malaria.
Thonsranoi K, et al.
International Journal of Clinical and Experimental Pathology, 8(11), 13996?14004-13996?14004 (2015)
Zhi-Zhao Ma et al.
International journal of clinical and experimental medicine, 8(8), 12834-12841 (2015-11-10)
Neural stem cells (NSCs) are multi-potent stem cells able to self-renew and generate immature and differentiated cell populations by asymmetric division. The NSCs are of considerable interest for cell replacement in neuro-degenerative diseases. NSCs are usually identified and expanded by

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