推薦產品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 69 kDa
物種活性
mouse, human
濃度
~1 mg/mL
技術
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... FOXO1(2308)
一般說明
Anti-FOXO1 Antibody detects endogenous levels of total FOXO1 protein.
FOXO1 (forkhead box O1) encodes a forkhead transcription factor that belongs to the Foxo subfamily. It is located on human chromosome 13q14. FOXO1 is abundantly expressed in adult pancreas and partially expressed in pancreatic β cells.
免疫原
The antiserum was produced against synthesized peptide derived from human FOXO1/3/4.
Immunogen Range: 15-64
Immunogen Range: 15-64
生化／生理作用
FOXO1 (forkhead box O1) blocks the separation of cell in fetal pancreatic progenitor cells. It controls the differentiation of adipocyte. It plays a major role in the development and multiplication of β cell. It plays an important role in transferring insulin signaling downstream of protein kinase B.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
Daitoku H, et al.
Proceedings of the National Academy of Sciences of the USA, 101(27), 10042-10047 (2004)
Forkhead Protein FoxO1 Acts as a Repressor to Inhibit Cell Differentiation in Human Fetal Pancreatic Progenitor Cells
Jiang Z, et al.
Journal of Diabetes Research, 2017 (2017)
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth
Kitamura T, et al.
The Journal of Clinical Investigation, 110(12), 1839-1847 (2002)
Dense pattern of embryonal rhabdomyosarcoma, a lesion easily confused with alveolar rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group
Rudzinski ER, et al.
American Journal of Clinical Pathology, 140(1), 82-90 (2013)
The forkhead transcription factor Foxo1 regulates adipocyte differentiation
Nakae J, et al.
Developmental Cell, 4(1), 119-129 (2003)
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