SAB4300425

Anti-GRIN2B (Ab-1474) antibody produced in rabbit

affinity isolated antibody

• 同義詞: Anti-MGC142178 antibody produced in rabbit, Anti-MGC142180 antibody produced in rabbit, Anti-NMDAR2B antibody produced in rabbit, Anti-NR2B antibody produced in rabbit, Anti-glutamate receptor, ionotropic, N-methyl D-aspartate 2B antibody produced in rabbit
• MDL號碼: MFCD00243314
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: ~190 kDa
• 物種活性: human, rat, mouse
• 濃度: 1 mg/mL
• 技術: indirect immunofluorescence: 1:100-1:200
• 同型: IgG
• 免疫原序列: (H-V-Y-E-K)
• NCBI登錄號: NP_000825.2
• UniProt登錄號: Q13224
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... GRIN2B(2904)

描述

一般說明

GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) codes for N-methyl d-aspartate receptor subtype 2B (GluN2B). It belongs to the N-methyl-D-aspartate receptor (NMDAR) gene family. It is located on human chromosome 12p13.1.

免疫原

Peptide sequence around aa. 1472-1476 (H-V-Y-E-K), according to the protein GRIN2B.

生化／生理作用

GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) plays an important role in the growth of neurons and is highly essential for the learning and memory. GRIN2B mutation is associated with neuropsychiatric and developmental disorders like schizophrenia, Parkinson′s disease and bipolar disorder.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

標靶描述

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.

外觀

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable