SAB4200590

Anti-WHAMM (C-terminal) Produced in rabbit

affinity isolated antibody

• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 形狀: buffered aqueous solution
• 分子量: ~100 kDa
• 物種活性: human
• 濃度: ~1 mg/mL
• 技術: immunoblotting: 1-2 μg/mL using whole extracts of HEK-293T cells overexpressing human WHAMM.
• UniProt登錄號: Q8TF30
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... WHAMM(123720)

描述

一般說明

WASP homologue associated with actin, membranes, and microtubules (WHAMM) is a nucleation promoting factor. It is located in the cis-Golgi and tubulo-vesicular membrane transport intermediates. WHAMM contains an N-terminal region, a coiled-coil region and a WCA region. It is located on the human chromosome at 15q25.2.

特異性

Anti- WHAMM (C-terminal) recognizes human WHAMM.

免疫原

peptide corresponding to the C-terminal region of human WHAMM , conjugated to KLH.

應用

Anti-WHAMM (C-terminal) produced in rabbit may be used in immunoblotting.

生化／生理作用

WASP homologue associated with actin, membranes, and microtubules (WHAMM) takes part in actin-related protein 2 & 3 (Arp2/3)-mediated actin polymerization, mediates Golgi membrane association and microtubule dynamics. It also takes part in the maintenance of Golgi structure and participates in vesicle transport between the endoplasmic reticulum and the Golgi apparatus.

外觀

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

儲存和穩定性

For continuous use, store at 2–8 °C for up to one month. For extended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable