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Merck
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SAB3700372

Sigma-Aldrich

Anti-Guinea Pig IgG (H+L)-Peroxidase antibody produced in goat

affinity isolated antibody, lyophilized powder

同義詞:

HRP

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

goat

共軛

peroxidase conjugate

抗體表格

affinity isolated antibody

抗體產品種類

secondary antibodies

無性繁殖

polyclonal

形狀

lyophilized powder

物種活性

guinea pig

技術

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

一般說明

The IgG (immunoglobulin G) structure possesses four polypeptide chains containing two identical γ heavy (H) chains and two identical κ or λ light (L) chains of 50kDa and 25kDa respectively. The chains are interlinked with a disulfide bond. Both the L and the H chains consist of a variable domain at the N-terminal. The C-terminal bears′ constant domains: three in H chain with a hinge region and one in the L chain. IgG contributes to 10−20% of plasma protein and is regarded as one of the most abundant serum protein. IgG antibody is enriched in mother′s milk.

特異性

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Guinea Pig IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Peroxidase, Anti-Goat Serum, Guinea Pig IgG and Guinea Pig Serum.

免疫原

Guinea Pig IgG whole molecule

生化/生理作用

IgG (immunoglobulin G) antibody protects against bacterial, fungal and viral infections. It helps in opsonization, complement fixation and antibody-dependent cell-mediated cytotoxicity. IgG antibody has its function similar to IgM antibody in complement system activation. IgG participates in hypersensitivity type II and type III. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

物理性質

Antibody format: IgG

外觀

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

重構

Reconstitute with 1.0 mL deionized water (or equivalent).

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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存取文件庫

IgG subclasses and allotypes: from structure to effector functions
Vidarsson G, et al.
Frontiers in Immunology, 5(4), 520-520 (2014)
Placental transfer of IgG subclasses in a Japanese population.
Hashira S, et al.
Pediatrics International, 42(4) (2000)
Specific IgG for cat allergens in patients with allergic conjunctivitis.
Miyama A, et al.
International Ophthalmology, 35(4), 575-586 (2015)

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