生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
rat, human, mouse
技術
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... WDR74(54663)
一般說明
WD repeat domain 74 (WDR74), also known as NOP seven-associated protein 1 (NSA1), is encoded by the gene mapped to human chromosome 11q12.3. The encoded protein is mainly localized in the nucleus and it contains six WD40 repeats.
免疫原
NSA1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human NSA1.
生化/生理作用
WD repeat domain 74 (WDR74) along with the nucleolar AAA-ATPase NVL2, plays a vital role in an early cleavage of the pre-rRNA processing pathway. It is also implicated in various biological processes, including cell cycle control and apoptosis. In mouse, this protein plays an essential role in RNA transcription, processing and/or stability during preimplantation development.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
聯結
The action of this antibody can be blocked using blocking peptide SBP3500152.
外觀
Supplied in PBS with 0.02% sodium azide.
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相關產品
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Genome-wide analysis of non-coding regulatory mutations in cancer
Weinhold N, et al.
Nature Genetics, 46(11), 1160-1160 (2014)
Genes Involved in Human Ribosome Biogenesis are Transcriptionally Upregulated in Colorectal Cancer
Mansilla F, et al.
Scholarly Research Exchange (2009)
Wdr74 Is Required for Blastocyst Formation in the Mouse
Maserati M, et al.
PLoS ONE, 6(7), e22516-e22516 (2011)
WDR74 participates in an early cleavage of the pre-rRNA processing pathway in cooperation with the nucleolar AAA-ATPase NVL2.
Hiraishi N, et al.
Biochemical and Biophysical Research Communications, 495(1), 116-123 (2018)
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