SAB2501804

Anti-CCL20 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• 同義詞: CKb4, LARC, MIP-3a, chemokine (C-C motif) ligand 20
• 分類程式碼代碼: 12352203

屬性

• 生物源: goat
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 物種活性: human, bovine, pig
• 技術: immunohistochemistry: suitable; indirect ELISA: suitable
• UniProt登錄號: P78556
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... CCL20(6364)

描述

一般說明

Chemokine ligand 20 (CCL20) is also called as liver and activation-regulated chemokine, macrophage inflammatory protein-3α (MIP-3α) or exodus-1. It is a cysteine−cysteine chemokine, that is located on human chromosome 2q36. It is expressed at high levels in serum or IgA1 and HMC incubation system. The CCL20 promoter region consists of a transcription start site, a nuclear factor (NF)-κB binding site, a CCAAT/enhancer-binding proteins binding site, an activator protein-1 binding sites and a specificity protein 1 (Sp1)-binding site.

免疫原

Peptide with sequence CLGYTDRILHPK, from the internal region of the protein sequence according toNP_004582.1; NP_001123518.1

生化／生理作用

Chemokine ligand 20 (CCL20) is chemotactic for immature dendritic cells, effector or memory CD4⁺T lymphocytes and B lymphocytes. CCR6 (C-C chemokine receptor type 6), the receptor of CCL20, plays a vital role in the progression of several diseases, such as tumors, rheumatoid arthritis, pneumococcal meningitis and human renal inflammation.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable