推薦產品
生物源
goat
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
canine, human, rat, mouse
技術
ELISA: suitable
flow cytometry: suitable
immunohistochemistry: suitable
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... DGAT2(84649)
一般說明
Diacylglycerol O-acyltransferase 2 (DGAT2) possesses one or two transmembrane domains and the amino- and carboxyl-terminal regions face the cytosol. The gene encoding it is localized on human chromosome 11q13.5 and has eight exons.
免疫原
Peptide with sequence C-KLEHPTQQDIDLYH from the internal region (near the C Terminus) of the protein sequence according to NP_115953.2.
生化／生理作用
Diacylglycerol O-acyltransferase 2 (DGAT2) is involved in the final step of triacylglycerol biosynthesis. It esterifies diacylglycerol to triacylglycerol. Overexpression of the protein has been associated with hepatic steatosis.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Liver fat reduction with niacin is influenced by DGAT-2 polymorphisms in hypertriglyceridemic patients.
Hu M
Journal of Lipid Research (2012)
Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene.
Nurminen R
Genes Chromosomes Cancer (2016)
Roles of Acyl-CoA:Diacylglycerol Acyltransferases 1 and 2 in Triacylglycerol Synthesis and Secretion in Primary Hepatocytes.
Li C
Arteriosclerosis, Thrombosis, and Vascular Biology (2015)
Justin Chun et al.
Journal of the American Society of Nephrology : JASN, 33(5), 889-907 (2022-03-03)
Two variants in the gene encoding apolipoprotein L1 (APOL1) that are highly associated with African ancestry are major contributors to the large racial disparity in rates of human kidney disease. We previously demonstrated that recruitment of APOL1 risk variants G1
Active Filters
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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