SAB1403609

Monoclonal Anti-BMP2, (C-terminal) antibody produced in mouse

clone 4B12, purified immunoglobulin, buffered aqueous solution

• 同義詞: BMP2A
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: mouse
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 4B12, monoclonal
• 形狀: buffered aqueous solution
• 分子量: antigen ~38.65 kDa
• 物種活性: human
• 技術: indirect ELISA: suitable; proximity ligation assay: suitable
• 同型: IgG2aκ
• NCBI登錄號: NM_001200
• UniProt登錄號: P12643
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... BMP2(650)

描述

一般說明

Bone morphogenetic protein 2 (BMP2) belongs to the transforming growth factor-β (TGF-β) superfamily. It is expressed in a variety of tissues such as heart, lung and dorsal aorta. The gene encoding this protein is localized on human chromosome 20p12.3.

免疫原

BMP2 (NP_001191, 283 a.a. ~ 396 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
QAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR

生化／生理作用

Bone morphogenetic proteins (BMPs) promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. During bone repair, BMP2 controls the expression of Runt-related transcription factor 2 (Runx2) and osterix (Osx), thereby enhancing migration, proliferation and osteogenic differentiation of mesenchymal stem cells. In addition to its osteogenic activity, BMP2 also plays an important role in cardiac morphogenesis.

外觀

Solution in phosphate buffered saline, pH 7.4

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable