S5439

Src human

≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution, histidine-tagged

• MDL號碼: MFCD03458574
• 分類程式碼代碼: 12352200
• NACRES: NA.32

屬性

• 重組細胞: expressed in baculovirus infected insect cells
• 化驗: ≥80% (SDS-PAGE)
• 形狀: buffered aqueous glycerol solution
• 分子量: 60 kDa
• 濃度: ~0.58 mg/mL protein (Bradford assay)
• UniProt登錄號: P12931
• 應用: cell analysis
• 運輸包裝: dry ice
• 儲存溫度: −70°C
• 基因資訊: human ... SRC(6714)

描述

一般說明

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) belongs to the family of non-receptor tyrosine kinases. It contains an amino-terminal domain, conserved Src-homology domains (SH2 and SH3), a tyrosine kinase domain and the carboxyl-terminus. The gene encoding this protein is localized on human chromosome 20q11.23.

應用

Human Src has been used to study the kinetics of Src entrapped in a series of different sol-gel derived materials.

生化／生理作用

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) phosphorylates membrane proteins and nucleoproteins and activates various intracellular signaling cascades. It has been associated with a number of human malignancies and cancers.

單位定義

One unit will phosphorylate one nmole of poly(Gly:Tyr) 4:1 per minute at pH 7.5 at 30°C.

外觀

Solution in 50 mM Tris pH 7.5, 0.05 mM EDTA, 1 mM DTT, 100 mM NaCl, 0.05% NP-40, and 50% glycerol.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable