生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous glycerol solution
用途
sufficient for 10 blots
物種活性
mouse, human, rat
技術
dot blot: suitable
western blot: 1:1,000 using rat brain lysate
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... SYT1(6857)
mouse ... Syt1(20979)
rat ... Syt1(25716)
一般說明
SYT1 (synaptotagmin-1) or phospho-Synaptotagmin is a calcium binding synaptic vesicle protein, that is located on chromosome 12q21. It is usually present in nerve cells.
免疫原
synthetic phosphopeptide corresponding to amino acids residues surrounding the serine 309 of synaptotagmin (Syt).
生化/生理作用
Synaptotagmin-1 (SYT1) is an essential factor for exocytosis, endocytosis and vesicular Ca2+/H+ antiport activity.
外觀
Solution in 10 mM HEPES, pH 7.5, 150 mM NaCl with 100 μg/mL BSA and 50% glycerol.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Transancestral mapping and genetic load in systemic lupus erythematosus
Langefeld CD, et al.
Nature Communications, 8 (2017)
Identification of a human synaptotagmin-1 mutation that perturbs synaptic vesicle cycling
Baker K, et al.
The Journal of Clinical Investigation, 125(4), 1670-1678 (2015)
Differential Membrane Binding Mechanics of Synaptotagmin Isoforms Observed in Atomic Detail
Vermaas JV and Tajkhorshid E
Biochemistry, 56(1), 281-293 (2017)
Salvatore Santamaria et al.
mAbs, 9(4), 595-602 (2017-03-18)
The potent aggrecanase ADAMTS-5 is constitutively secreted by chondrocytes, but it is rapidly endocytosed in normal cartilage via the cell surface endocytic receptor LRP1. Therefore it is difficult to detect the total ADAMTS-5 activity produced. In this study, we isolated
Anna-Carina Weiss et al.
Development (Cambridge, England), 141(17), 3420-3430 (2014-08-21)
The vesico-ureteric junction (VUJ) forms through a complex developmental program that connects the primordium of the upper urinary tract [the nephric duct (ND)] with that of the lower urinary tract (the cloaca). The signals that orchestrate the various tissue interactions
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