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Merck
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S3072

Sigma-Aldrich

Spiramycin adipate

同義詞:

Spiramycin hexanedioate

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About This Item

EC號碼:
MDL號碼:
分類程式碼代碼:
51101500

形狀

powder

效力

3948 I.U. per mg

儲存條件

(Keep container tightly closed in a dry and well-ventilated place.)

顏色

off-white

抗生素活性譜

Gram-positive bacteria

作用方式

protein synthesis | interferes

儲存溫度

2-8°C

一般說明

Chemical structure: macrolide

應用

Spiramycin is a macrolide antibiotic that is commonly used to treat infections of soft tissues. It has been used to treat bronchopulmonary infections in adults and has been used to study septicemia in mice .

生化/生理作用

Spiramycin is a 16-membered ring macrolide antibiotic from Streptomyces ambofaciens. It inhibits bacterial protein synthesis at the level of peptidy-tRNA dissociation from ribosomes. It is mainly used against Gram-positive bacteria.

其他說明

This product is a mixture of spiramycins I, II, and III.
Keep container tightly closed in a dry and well-ventilated place.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Acute bronchopulmonary infections: treatment with i.v. spiramycin.
F Vachon and S Kernbaum
Chemotherapia, 6, 282-285 (1987)
O Rolin et al.
Pathologie-biologie, 34(5), 476-478 (1986-05-01)
Experimental septicemia was induced in mice by intraperitoneal injection of 10 to 100 lethal doses of Staphylococcus aureus and Streptococcus pneumoniae. Animals were treated by a mixture of adipic acid and spiramycin (subcutaneous route) or by spiramycin base (oral route)

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