跳轉至內容
Merck
全部照片(1)

文件

S2941

Sigma-Aldrich

SKF-75670 hydrobromide

>98% (HPLC), solid

同義詞:

7,8-dihydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide

登入查看組織和合約定價
全部照片(1)

About This Item

經驗公式（希爾表示法）:
C17H19NO2 · HBr
CAS號碼:
62717-63-9
分子量：:
350.25
MDL號碼:
MFCD11045981
分類程式碼代碼:
12352200
PubChem物質ID:
24278700

化驗

>98% (HPLC)

形狀

solid

顏色

white

溶解度

DMSO: soluble 12 mg/mL
H2O: insoluble

SMILES 字串

Br.CN1CCc2cc(O)c(O)cc2C(C1)c3ccccc3

InChI

1S/C17H19NO2.BrH/c1-18-8-7-13-9-16(19)17(20)10-14(13)15(11-18)12-5-3-2-4-6-12;/h2-6,9-10,15,19-20H,7-8,11H2,1H3;1H

InChI 密鑰

KWTPHNVUAVFKGB-UHFFFAOYSA-N

基因資訊

human ... DRD1(1812)

應用

SKF-75670 may be used in dopamine and cocaine-mediated cell signaling studies.

生化／生理作用

SKF-75670 is a selective dopamine D1 receptor agonist but with lower efficacy. It also acts as cocaine antagonist and alters the behavioral effects of cocaine in squirrel monkeys.
Atypical D1 dopamine receptor agonist. Displays antagonist activity in vitro and agonist activity in vivo.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

已經擁有該產品？

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

R D Spealman et al.
Psychopharmacology, 133(3), 283-292 (1997-11-15)
Dopamine D1 agonists differing in efficacy with respect to stimulation of adenylate cyclase activity and other in vitro and in vivo criteria were evaluated for their capacity to modulate the behavioral effects of cocaine in squirrel monkeys. Monkeys were trained
P H Andersen et al.
European journal of pharmacology, 188(6), 335-347 (1990-06-12)
Dopamine receptor selectivity was investigated for a number of dopamine receptor agonists. In vitro, the benzazepine derivatives, e.g., SKF 38393 and SKF 75670 as well as the isoquinoline derivatives, SKF 89626 and SKF 89615, were D1 receptor-selective. All other compounds

我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務