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Key Documents

S2320

Sigma-Aldrich

Anti-SFRS2 antibody produced in rabbit

affinity isolated antibody, PBS solution, contains 0.09% sodium azide as preservative

同義詞:

Anti-Splicing Factor Arginine/serine-rich 2

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About This Item

MDL號碼:
分類程式碼代碼:
12352203

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

PBS solution

分子量

antigen 25.6 kDa

包含

0.09% sodium azide as preservative

物種活性

human

技術

immunohistochemistry: suitable
western blot: suitable

儲存溫度

−20°C

基因資訊

human ... SFRS2(6427)
mouse ... Sfrs2(20382)
rat ... Sfrs2(494445)

免疫原

synthetic peptide from the N-terminal region of SFRS2 conjugated to KLH.

應用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

標靶描述

SFRS2 (Splicing Factor Arginine/Serine-rich 2), alsoknown as PR264, SC35 (splicing component 35), and SRp30b, is a member of the SR protein family of splicing factors. SFRS2 regulates alternative splicing of pre-mRNA.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves


分析證明 (COA)

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Matthew J Yousefzadeh et al.
EBioMedicine, 36, 18-28 (2018-10-04)
Senescence is a tumor suppressor mechanism activated in stressed cells to prevent replication of damaged DNA. Senescent cells have been demonstrated to play a causal role in driving aging and age-related diseases using genetic and pharmacologic approaches. We previously demonstrated
Rayna Rosati et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 24(24), 6509-6522 (2018-09-07)
Testosterone suppression in prostate cancer is limited by serious side effects and resistance via restoration of androgen receptor (AR) functionality. ELK1 is required for AR-dependent growth in various hormone-dependent and castration-resistant prostate cancer models. The amino-terminal domain of AR docks
Jana Kralovicova et al.
Nucleic acids research, 42(12), 8161-8173 (2014-06-20)
Splice-switching oligonucleotides (SSOs) have been widely used to inhibit exon usage but antisense strategies that promote removal of entire introns to increase splicing-mediated gene expression have not been developed. Here we show reduction of INS intron 1 retention by SSOs

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