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RES6007H-A7

SAFC

HEPES钠盐 钠盐

同義詞:

4-(2-羟乙基)哌嗪-1-乙磺酸 钠盐, N-(2-羟乙基)哌嗪-N′-(2-乙磺酸) 钠盐

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About This Item

經驗公式(希爾表示法):
C8H17N2NaO4S
CAS號碼:
分子量::
260.29
EC號碼:
MDL號碼:
分類程式碼代碼:
12161700
NACRES:
NA.21

生物源

synthetic

形狀

powder

技術

cell culture | mammalian: suitable

雜質

Endotoxin, microbial, and trace metals; tested

有用的pH值範圍

6.8-8.2

pKa (25 °C)

7.5

適合性

suitable for manufacturing use

異物活動

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES 字串

[Na+].OCCN1CCN(CC1)CCS([O-])(=O)=O

InChI

1S/C8H18N2O4S.Na/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;/h11H,1-8H2,(H,12,13,14);/q;+1/p-1

InChI 密鑰

RDZTWEVXRGYCFV-UHFFFAOYSA-M

尋找類似的產品? 前往 產品比較指南

一般說明

我们用于生物制药加工的SAFC®系列优质原料经过严格的质量控制流程,配合记录文件和技术专长帮助我们的客户达到M-Clarity 计划规定的要求

M-Clarity 计划

缓冲液质量是生物制药工艺成功的关键,因为缓冲液几乎在每一个生产步骤中都是必不可少的。

我们广泛的缓冲材料产品线经过妥善管控,可根据您的需求量身定制。从低风险应用的非 GMP 等级,到高风险应用的 IPEC-PQG GMP标准,我们的产品可满足您的所有制造需求。

應用

HEPES是一种生物缓冲液,通常被称为Good′s缓冲液。HEPES钠盐与HEPES结合使用,是最常用的生物缓冲液配方,该缓冲液的pKa为7.31,与7.36的生理pH对应。HEPES钠盐被认为是对培养细胞系无毒的一种物质高度可溶于水并可为溶液提供高澄清度。

MES那样用于细胞培养基、生物制药缓冲制剂上游和下游以及诊断试剂。

包裝

该产品有以下包装尺寸:
RES6007H-A701X: 100g容器
RES6007H-A702X: 1kg容器
RES6007H-A704X: 10kg容器
RES6007H-A705X: 25kg容器

法律資訊

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

取代透過

產品號碼
描述
訂價

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Peng Yang
Macromolecular bioscience, 12(8), 1053-1059 (2012-06-19)
When lysozyme is dissolved in a neutral HEPES buffer solution (pH = 7.4) with 0.001-0.050 M TCEP added, a fast phase transition process occurs and the resulting novel fiber-like hierarchical supramolecular assemblies made by primary spherical-particle aggregation can function as a "superglue"
Anca G Delgado et al.
Microbial cell factories, 11, 128-128 (2012-09-15)
Buffering to achieve pH control is crucial for successful trichloroethene (TCE) anaerobic bioremediation. Bicarbonate (HCO3-) is the natural buffer in groundwater and the buffer of choice in the laboratory and at contaminated sites undergoing biological treatment with organohalide respiring microorganisms.
Jihye Park et al.
The Analyst, 137(19), 4411-4414 (2012-08-07)
We have developed a quickly responsive, and specific fluorescent assay for the detection of Au(III) on the basis of the formation of gold nanoparticles in the presence of HEPES, which cleave the C-I bond of I-BODIPY 1 to yield the
Tina Vognsen et al.
Biochemical and biophysical research communications, 420(1), 188-192 (2012-03-15)
The crystal structure of the NTF2-like domain of the Drosophila homolog of Ras GTPase SH3 Binding Protein (G3BP), Rasputin, was determined at 2.7Å resolution. The overall structure is highly similar to nuclear transport factor 2: It is a homodimer comprised
S Hugel et al.
British journal of pharmacology, 166(8), 2402-2416 (2012-03-29)
Artificial buffers such as HEPES are extensively used to control extracellular pH (pH(e) ) to investigate the effect of H(+) ions on GABA(A) receptor function. In neurones cultured from spinal cord dorsal horn (DH), dorsal root ganglia (DRG) and cerebellar

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

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