推薦產品
物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
輸入
sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 30 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... FGF19(9965)
一般說明
该ELISA抗体对可检测人成纤维细胞生长因子19。
應用
仅供研究使用。不可用于诊断操作。
请参考附带的一般ELISA试剂盒操作程序（夹心、竞争性 & 间接ELISA）
请参考附带的一般ELISA试剂盒操作程序（夹心、竞争性 & 间接ELISA）
生化／生理作用
成纤维细胞生长因子（FGF）19通过激活FGF受体4来控制靶器官中的胆汁酸、脂肪酸、葡萄糖和磷酸盐代谢。FGF19通过激活胰岛素非依赖性内分泌途径调节肝蛋白和糖原代谢。在糖尿病小鼠中，FGF19降低了血清葡萄糖和甘油三酸酯的水平。该基因的过度表达导致肝细胞癌（HCC）的发展。
其他說明
本产品提供样本检验报告。
请在批号对应的文本框中输入样品 一词。
请在批号对应的文本框中输入样品 一词。
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Helene Johansson et al.
Frontiers in endocrinology, 11, 554922-554922 (2021-03-12)
Bile acids (BAs) are detergents essential for intestinal absorption of lipids. Disruption of BA homeostasis can lead to severe liver damage. BA metabolism is therefore under strict regulation by sophisticated feedback mechanisms. The hormone-like protein Fibroblast growth factor 19 (FGF19)
Weihua Chen et al.
Clinical reviews in allergy & immunology, 58(1), 25-38 (2019-03-23)
Accumulation of bile acids (BAs) contributes significantly to the pathogenesis of primary biliary cholangitis (PBC). Here, we sought to systematically characterize the serum and fecal BA profiles and the linkage between BAs and gut microbiota in PBC. The serum and
Kai Wang et al.
Cell reports, 26(1), 222-235 (2019-01-04)
We demonstrated the metabolic benefits of Parabacteroides distasonis (PD) on decreasing weight gain, hyperglycemia, and hepatic steatosis in ob/ob and high-fat diet (HFD)-fed mice. Treatment with live P. distasonis (LPD) dramatically altered the bile acid profile with elevated lithocholic acid (LCA)
Aze Wilson et al.
Scientific reports, 10(1), 1866-1866 (2020-02-07)
Bile acids are endogenous ligands of nuclear receptors pregnane X (PXR) and farnesoid X (FXR). PXR and FXR regulate pathways that are impaired in inflammatory bowel disease (IBD). Decreases in PXR and FXR activity are documented in IBD; however reasons
Xiangdong Zhao et al.
Molecular carcinogenesis, 57(11), 1616-1625 (2018-08-04)
Although genetic amplification and overexpression of the fibroblast growth factor 19 (FGF19) gene are found in human breast cancer, mechanisms that contribute to such functional alterations remain elusive. We report here that high expression of FGF19 is associated with the
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務