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Merck
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重要文件

RAB0160

Sigma-Aldrich

人EGFR/ ErbB1 ELISA试剂盒

for serum, plasma, cell culture supernatants and urine

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About This Item

分類程式碼代碼:
41116158
NACRES:
NA.32
暫時無法取得訂價和供貨情況

物種活性

human

包裝

kit of 96 wells (12 strips x 8 wells)

技術

ELISA: suitable
capture ELISA: suitable

輸入

sample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 pg/mL
standard curve range: 2.74-2000 pg/mL

檢測方法

colorimetric

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... EGFR(1965)

相關類別

一般說明

Epidermal growth factor receptor (EGFR) is a member of the epidermal growth factor receptor tyrosine kinase (RTK) family. It is a single-chain transmembrane glycoprotein. EGFR comprises an extracellular ligand-binding ectodomain, a short juxtamembrane section, a transmembrane domain, a tyrosine kinase domain, tyrosine-containing C-terminal tail.[1] Overexpression of EGFR is observed in breast cancer cells.[2]

免疫原

Recombinant Human EGFR

應用

Human EGFR / ErbB1 ELISA Kit has been used in the estimation of epidermal growth factor receptors (EGFR) from human epithelial cells.[3] It has also been used in the detection of EGFR from patient plasma/serum and exosomes isolated from human prostate cancer cells LNCaP xenografts.[4]

其他說明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

套裝中的組件也可單獨購買

產品號碼
描述
SDS
  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

象形圖

Corrosion
GHS05

訊號詞

Warning

危險聲明

H290

防範說明

P234 - P390

危險分類

Met. Corr. 1

儲存類別代碼

8A - Combustible corrosive hazardous materials

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
0129F0205
0925F0205
0814F0205
0604F0205
SAMPLE

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存取文件庫

Jiao-Jiao Yu et al.
Nature communications, 11(1), 3660-3660 (2020-07-23)
High expression or aberrant activation of epidermal growth factor receptor (EGFR) is related to tumor progression and therapy resistance across cancer types, including non-small cell lung cancer (NSCLC). EGFR tyrosine kinase inhibitors (TKIs) are first-line therapy for NSCLC. However, patients
Lingmei Huang et al.
Scientific reports, 7(1), 11084-11084 (2017-09-13)
Biomass fuel smoke is thought to contribute to chronic obstructive pulmonary disease, which is characterized by mucous cell metaplasia and enhanced mucus secretion. We investigated the effect of particulate matter (PM) with a diameter <2.5 μm (PM2.5) from wood smoke
Martin Siegemund et al.
Scientific reports, 8(1), 7808-7808 (2018-05-19)
Single-chain formats of TNF-related apoptosis inducing ligand (scTRAIL) can serve as effector components of tumour-associated antigen-targeted as well as non-targeted fusion proteins, being characterized by high tumour cell-specific induction of apoptosis through death receptor activation. We studied the suitability of
Takumi Fujiwara et al.
Cancers, 12(10) (2020-10-25)
Background: Lung cancer is the leading cause of mortality for cancer worldwide. A point mutation in exon 21 of the epidermal growth factor receptor resulting in the substitution of arginine for leucine at position 858 (L858R) is a frequent cause
M J Wieduwilt et al.
Cellular and molecular life sciences : CMLS, 65(10), 1566-1584 (2008-02-09)
The epidermal growth factor family of receptor tyrosine kinases (ErbBs) plays essential roles in regulating cell proliferation, survival, differentiation and migration. The ErbB receptors carry out both redundant and restricted functions in mammalian development and in the maintenance of tissues
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