The Positive Control functions as a system control to verify the functionality of the kit components. The resulting OD will not be utilized in any calculations. Any signal within the standard curve range that demonstrates competition in the assay indicates that the assay is performing as anticipated.
species reactivity
mouse, human, rat
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, enzyme immunoassay: suitable
input
sample type cell lysate
sample type culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 2.62 pg/mL
standard curve range: 0.1-1000 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... AGT(183)
General description
血管紧张素 II 酶联免疫分析 (EIA) 试剂盒是一种基于竞争酶联免疫分析原理的血管紧张素 II 多肽体外定量检测方法。EIA-ANGII-1 理论上可以检测所有活性血管紧张素，包括 ANGI、ANGII、ANGIII 和 ANGIV。但是，它不能检测无活性的血管紧张素原。
Immunogen
血管紧张素 II，合成肽
Application
请参阅随附常规ELISA试剂盒 操作步骤（夹心式、竞争性 & 间接ELISA）
Biochem/physiol Actions
体外研究 表明，机械牵张诱导的血管紧张素 II释放在介导牵张诱导的肥大反应中起着至关重要的作用。血管紧张素 II参与维持血压，在高血压和心血管疾病的病理生理过程中具有重要作用。血管紧张素 II在血管平滑肌细胞的生长诱导、细胞迁移和有丝分裂中也有重要角色。它可增强成纤维细胞中 I 类型和 III 型胶原的生成，导致血管壁和心肌增厚以及纤维化。血管紧张素 II 基因的变异增加了心肌梗死、高血压和左心室肥厚的风险。血管紧张素 II 的表达与心力衰竭、心脏重塑、糖尿病以及动脉损伤的增殖和炎症反应有关。血管紧张素 II 转换酶抑制剂或血管紧张素 II 受体拮抗剂等药物可用于治疗血管紧张素 II 诱导的高血压和充血性心力衰竭。
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本產品 | |||
|---|---|---|---|
| description for serum, plasma, culture supernatant and cell lysates | description for cell culture supernatants, plasma, and serum samples | description ≥93% (HPLC), powder | description Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution |
| species reactivity mouse, human, rat | species reactivity human | species reactivity - | species reactivity human |
| technique(s) ELISA: suitable, enzyme immunoassay: suitable | technique(s) ELISA: suitable | technique(s) cell culture | mammalian: suitable | technique(s) immunoblotting: 0.04-0.4 μg/mL, immunohistochemistry: 1:20-1:50 |
| detection method colorimetric | detection method colorimetric | detection method - | detection method - |
| Gene Information human ... AGT(183) | Gene Information human ... AGT(183) | Gene Information human ... AGT(183) | Gene Information human ... AGT(183) |
| assay range inter-assay cv: <15% | assay range inter-assay cv: <12% | assay range - | assay range - |
| input sample type cell lysate | input sample type serum sample(s) | input - | input - |
警示詞
Warning
危險代碼
預防性聲明
Hazard Classifications
Met. Corr. 1
存儲類別/等級
10 - Combustible liquids
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What is the expected response for the positive control in the Human Angiotensin II EIA (RAB0010)?
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