跳轉至內容
Merck
全部照片(2)

重要文件

檢視所有文件

R7632

Sigma-Aldrich

视黄醇

Retinol
1 of 1 reviewers received a sample product or took part in a promotion

synthetic, ≥95% (HPLC), (Powder or Powder with Lumps)

同義詞:

全反式-3,7-二甲基-9-(2,6,6-三甲基-1-环己烯-1-基)-2,4,6,8-壬四烯-1-醇, 抗干眼醇, 维生素 A, 维生素 A 醇, 维生素 A1

登入查看組織和合約定價
全部照片(2)

About This Item

經驗公式（希爾表示法）:
C20H30O
CAS號碼:
68-26-8
分子量：:
286.45
Beilstein:
403040
EC號碼:
200-683-7
MDL號碼:
MFCD00001552
分類程式碼代碼:
12352205
eCl@ss:
34058018
PubChem物質ID:
24899395
NACRES:
NA.79
暫時無法取得訂價和供貨情況

生物源

synthetic

化驗

≥95% (HPLC)

形狀

(Powder or Powder with Lumps)

比活性

~2700 U/mg

技術

HPLC: suitable

顏色

yellow to very dark yellow, to Very Dark Orange

mp

61-63 °C (lit.)

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO)=C(C)CCC1

InChI

1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+

InChI 密鑰

FPIPGXGPPPQFEQ-OVSJKPMPSA-N

尋找類似的產品？ 前往 產品比較指南

相關類別

一般說明

视黄醇又称维生素A醇，是维生素A的主要循环形式。它不具有生物活性。视黄醇又称全反式视黄醇，是一种带有环己烯基环的20碳分子，具有带四个双键（反式构型）的侧链和一个醇端基。[1]

應用

视黄醇已被用于：
  • HepG2细胞中全反式-视黄酸的合成。[2]
  • 研究视黄醇对作为类器官培养的鼠正常结肠细胞生长的影响。[3]
  • 测定细胞中维生素A的标准品。[4]
  • 作为体外睾丸器官培养和精子发生的成分确定培养基的成分。[5]

生化／生理作用

视黄醇及其衍生物有抗衰老特性。另外，它还起抗皱剂的作用。然而，由于对光不稳定并具有皮肤刺激性，它没有被广泛用于化妆品配方。[6]视黄醇可用于治疗包括光衰老在内的皮肤病。它的缺乏与干燥症和滤泡性角化过度症的发展有关。[1]
视黄醇是活性类视黄醇的前体。它可转化为视黄醛，然后再转化为视黄酸。All-trans及9-cis-视黄酸是核受体、视黄酸受体（RAR）和类视黄醇X受体（RXR）的配体。这些受体是多种基因的转录调控因子。[7]

包裝

无底玻璃瓶。内含物装在插入的融合锥内。
防光玻璃小瓶。

象形圖

Health hazardExclamation mark
GHS08,GHS07

訊號詞

Danger

危險分類

Aquatic Chronic 4 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 1

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
BCCL7122
BCCL8551
BCCM6917
BCCL1179
BCCM5486

未看到正確版本？

如果您需要一個特定的版本，您可以透過批號來尋找特定憑證。

搜尋 COA

已經擁有該產品？

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Insulin regulates retinol dehydrogenase expression and all-trans-retinoic acid biosynthesis through FoxO1.
Obrochta KM et al.
The Journal of Biological Chemistry, 290, 7259-7259 (2015)
Retinol Promotes In Vitro Growth of Proximal Colon Organoids through a Retinoic Acid-Independent Mechanism.
Matsumoto T et al.
PLoS ONE, 11, e0162049-e0162049 (2016)
In vitro mouse spermatogenesis with an organ culture method in chemically defined medium.
Sanjo H, et al.
PLoS ONE, 13 (2018)
Understanding the physiological role of retinol-binding protein in vitamin A metabolism using transgenic and knockout mouse models.
Quadro L et al.
Molecular Aspects of Medicine, 24, 421-421 (2003)
Yuanchao Li et al.
The journal of headache and pain, 17, 49-49 (2016-05-07)
As a complex nervous system disease, migraine causes severe healthy and social issues worldwide. Valproate (VPA) is a widely used treatment agent against seizures and bipolar disorder, and its function to alleviate damage due to migraine has also been verified
查看所有相關論文

條款

HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

1 Review This action will navigate to reviews.

Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

Reviews

1 of 1 reviewers received a sample product or took part in a promotion

Active Filters

  1. Farmington, CT
    • Review 1
    • Votes 0
    5 out of 5 stars.

    Reliable and fast

    The product is of high quality, and works to my satisfaction. The delivery was fast.

    Helpful?

我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務