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品質等級
化驗
≥98% (HPLC)
形狀
solution
濃度
100 mg/mL in ethanol: isopropanol (95:5)
抗生素活性譜
Gram-negative bacteria
Gram-positive bacteria
作用方式
protein synthesis | interferes
運輸包裝
dry ice
儲存溫度
−20°C
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應用
氯霉素是一种合成抗生素，从委内瑞拉链霉菌菌株中分离出来。 它通常以10-20 μg/mL的浓度用于分子生物学应用中的细菌选择，并作为含有氯霉素抗性基因的转化细胞的选择剂。
生化／生理作用
作用机制：氯霉素通过与50S核糖体亚基结合并阻止氨酰基tRNA附着于核糖体来阻断肽基转移酶步骤，从而抑制细菌蛋白质的合成。 它还抑制线粒体和叶绿体蛋白的合成以及（p）ppGpp的核糖体形成，从而抑制rRNA的转录。
耐药性机制：使用氯霉素乙酰转移酶会使产物乙酰化并使其失活。
抗菌谱：这是一种针对革兰氏阳性和革兰氏阴性细菌的广谱抗生素，主要用于眼科和兽医目的。
耐药性机制：使用氯霉素乙酰转移酶会使产物乙酰化并使其失活。
抗菌谱：这是一种针对革兰氏阳性和革兰氏阴性细菌的广谱抗生素，主要用于眼科和兽医目的。
包裝
10ml
準備報告
该产品是在乙醇：异丙醇（95:5）中制备的100 mg/mL溶液。 干冰运输，-20℃下保存。
其他說明
保存于密闭容器内，置于干燥通风处。打开的容器必须小心地重新密封，并保持直立以防止泄漏。储存等级（TRGS 510）：易燃液体“）
訊號詞
Danger
危險分類
Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
57.2 °F - closed cup
閃點（°C）
14.0 °C - closed cup
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分析證明 (COA)
Lot/Batch Number
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