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Merck
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重要文件

PRS2283

Sigma-Aldrich

抗-RIP3 兔抗

affinity isolated antibody

同義詞:

抗-受体相互作用丝氨酸苏氨酸激酶 3

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41
暫時無法取得訂價和供貨情況

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

分子量

predicted mol wt 57 kDa

物種活性

rat, human, mouse

技術

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

mouse ... Ripk3(56532)

免疫原

对应于鼠RIP氨基酸473-486的肽。

應用

成功使用该抗体的应用以及相关同行评审论文如下所示。
免疫细胞化学(1 篇)

聯結

可通过封闭肽SBP2283阻断此抗体的作用。

外觀

溶剂为含有0.02%叠氮化钠的磷酸盐缓冲盐水

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、体外或体内治疗用途,或人类或动物任何类型的消费或使用。

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產品號碼
描述
訂價

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Xia-Lian Wu et al.
Nature communications, 12(1), 1627-1627 (2021-03-14)
RIPK3 amyloid complex plays crucial roles during TNF-induced necroptosis and in response to immune defense in both human and mouse. Here, we have structurally characterized mouse RIPK3 homogeneous self-assembly using solid-state NMR, revealing a well-ordered N-shaped amyloid core structure featured
Imene Jaadane et al.
Scientific reports, 10(1), 6733-6733 (2020-04-23)
Exposure Limit Values (ELV) for artificial lighting were defined in order to prevent light-induced damage to the retina. The evaluation of the lighting devices include the correction of their spectra by the B(λ) function or blue light hazard function, representing
Lvshuang Liao et al.
Acta biochimica et biophysica Sinica, 49(10), 879-889 (2017-10-06)
Receptor-interacting protein 3 (RIP3) is an essential component of the necroptosis signaling pathway. Phosphorylation of its downstream target, mixed lineage kinase domain-like protein (MLKL), has been proposed to induce necroptosis by initiating Ca2+ influx. Our previous studies have shown that
Xiaofei Chen et al.
British journal of pharmacology, 176(12), 2095-2108 (2019-03-03)
Necroptosis is a form of programmed, caspase-independent, cell death, mediated by receptor-interacting protein kinases, RIPK1 and RIPK3, and the mixed lineage kinase domain-like (MLKL). Necroptosis contributes to the pathophysiology of various inflammatory, infectious, and degenerative diseases. Thus, identification of low
Justyna Sosna et al.
Molecular and cellular biology, 36(20), 2626-2644 (2016-08-17)
Recently, a type of regulated necrosis (RN) called necroptosis was identified to be involved in many pathophysiological processes and emerged as an alternative method to eliminate cancer cells. However, only a few studies have elucidated components of TRAIL-mediated necroptosis useful

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