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P4506

Sigma-Aldrich

磷酸二酯酶I 来源于西部菱背响尾蛇 (西部菱斑响尾蛇)

Type IV, crude dried venom

同義詞:

5'-核酸外切酶, 寡核苷酸5′-核苷酸降解酶

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About This Item

酶委員會編號:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54

種類

Type IV

品質等級

形狀

crude dried venom

儲存溫度

−20°C

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一般說明

Research area: Cell signalingPhosphodiesteraseI (PDEI) exists in three isoforms PDE1A,PDE1B, and PDE1C(2) that are locatedin cardiovascular, central nervous system, and other organs.

應用

本文用西方响尾蛇(Crotalus atrox)的磷酸二酯酶I分析了磷酸二酯酶I对中性粒细胞内钙浓度的影响。其也可与其他酶联合用于测定磷酸酶的活性。
磷酸二酯酶 (PDE) 是一种用来破坏磷酸二酯键的酶。磷酸二酯酶 I,产品 P4506 来自西部响尾蛇,用于磷酸二酯酶激活试验钙调素。加入该物质以水解AMP。其是一种膜结合糖蛋白,用于催化多种核苷酸多聚磷酸盐的水解。

生化/生理作用

磷酸二酯酶 I 破坏磷酸二酯键并催化各种核苷酸多磷酸盐的水解。通过磷脂酰肌醇特异性磷脂酶 C 从真核质膜释放磷酸二酯酶 I

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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