生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
human
濃度
~1 mg/mL
技術
western blot: 1:1,000-1:2,000
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... NANOG(79923)
mouse ... Nanog(71950)
rat ... Nanog(414065)
一般說明
Nanog homeobox (NANOG) is a 305 amino acid transcription factor. It is expressed in many types of cancers.
免疫原
synthetic peptide corresponding to an internal sequence of human Nanog.
生化／生理作用
Nanog homeobox (NANOG) works with pluripotency factors like sex determining region Y-box 2 (SOX2). It is involved in conserving the pluripotency and self-renewal properties of embryonic stem cells. NANOG also associates with the c-Jun promoter.
外觀
solution in phosphate buffered saline, containing 0.02% sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
NANOG upregulates c-Jun oncogene expression through binding the c-Jun promoter.
Lin Y
Molecular Carcinogenesis, 54(11), 1407-1416 (2015)
Shuai Gong et al.
Molecular carcinogenesis, 54(9), 679-687 (2015-05-28)
As one of the key pluripotency transcription factors, NANOG plays a critical role in maintaining the self-renewal and pluripotency in normal embryonic stem cells. Recent data indicate that NANOG is expressed in a variety of cancers and its expression correlates
Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells.
Hayashi Y
Proceedings of the National Academy of Sciences of the USA, 112(15), 4666-4671 (2015)
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