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MAK184

Sigma-Aldrich

琥珀酸检测试剂盒（比色法）

Sufficient for 100 Colorimetric tests

同義詞:

琥珀酸检测试剂盒

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About This Item

EC號碼:
205-778-7
分類程式碼代碼:
12161503
NACRES:
NA.84
暫時無法取得訂價和供貨情況

應用

cosmetics
food and beverages

檢測方法

colorimetric

相關疾病

cardiovascular diseases; immunological diseases

儲存溫度

−20°C

一般說明

琥珀酸（琥珀酸）是柠檬酸循环中间体，在将电子传递到线粒体电子传递链中起作用。[1][2]它还在先天免疫信号传导中起作用，并在炎症期间诱导 IL-1β 产生。琥珀酸盐经常用于治疗高血压。[3]琥珀酸盐测量可用于研究其代谢、免疫和治疗活性。

應用

琥珀酸检测试剂盒（比色法）已用于测量琥珀酸的浓度。[4][5]

適合性

适于测定不同生物样品内的琥珀酸，如细胞和组织培养上清液以及酒类等液态样品。

原則

琥珀酸检测试剂盒（比色法）是一种高灵敏度检测法，用于测定各种样品中的琥珀酸盐水平（范围为 2-10 nmole/孔）。琥珀酸浓度通过偶联酶反应测定，其产生与存在的琥珀酸盐成比例的比色（450nm）产物。

僅套裝組件

產品號碼
描述
  • Succinate Assay Buffer
  • Succinate Converter
  • Succinate Enzyme Mix
  • Succinate Substrate Mix
  • Succinate Developer
  • Succinate Standard

象形圖

Health hazardCorrosion
GHS08,GHS05

訊號詞

Danger

危險聲明

H314,H334

危險分類

Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
8G27K06490
7A21K06490
4C08K06490
4A18K06490
3B02K06490

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存取文件庫

VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism.
Li J, et al.
Nature Communications, 8(1), 1322-1322 (2017)
DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism.
Shen J, et al.
JCI insight, 2(12) (2017)
Metoprolol succinate extended release/hydrochlorothiazide combination tablets.
Hainer JW and Jennifer S
Vascular Health, 3(3), 279-279 (2007)
Yurong Zhang et al.
Redox biology, 28, 101365-101365 (2019-11-11)
Though succinate accumulation is associated with reactive oxygen species (ROS) production and neuronal injury, which play critical roles in epilepsy, it is unclear whether succinate accumulation contributes to the onset of epilepsy or seizures. We sought to investigate changes in
Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis.
Tretter L, et al.
Biochimica et Biophysica Acta - Bioenergetics, 1857(8), 1086-1101 (2016)
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Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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