推薦產品
品質等級
化驗
≥85% (HPLC)
形狀
oil
顏色
clear light yellow
應用
metabolomics
vitamins, nutraceuticals, and natural products
儲存溫度
2-8°C
SMILES 字串
COc1cc(CC=C)cc2OCOc12
InChI
1S/C11H12O3/c1-3-4-8-5-9(12-2)11-10(6-8)13-7-14-11/h3,5-6H,1,4,7H2,2H3
InChI 密鑰
BNWJOHGLIBDBOB-UHFFFAOYSA-N
一般說明
Myristicin, a phenylpropene, is an essential oil component.[1] It has anticholinergic and psychotropic activities.[2] Myristicin blocks cytochrome P450 monooxygenases, which detoxifies furanocoumarins.[1] It functions as a serotonin receptor agonist and hallucinogenic agent.[2] Myristicin stimulates glutathione S-transferase activity and might function as a chemopreventive agent.[3] It acts as a precursor for the metabolite 3,4- methylenedioxymethamphetamine (MDMA).[4]
應用
Myristicin from parsley leaf oil has been used to study competitive and uncompetitive inhibition of ACP (acid phosphatase) and ALP (alkaline phosphatase).[5]
生化／生理作用
Myristicin induces the expression of glutathione S-transferase and cytochrome P450 (Cyp1a-1) in liver cells. May enhance detoxification of carcinogenic substances.
訊號詞
Warning
危險聲明
危險分類
STOT SE 3
標靶器官
Central nervous system
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Myristicin: a potential cancer chemopreventive agent from parsley leaf oil
Zheng GQ, et al.
Journal of Agricultural and Food Chemistry, 40(1), 107-110 (1992)
H G Jeong et al.
Biochemical and biophysical research communications, 233(3), 619-622 (1997-04-28)
Mouse hepatoma Hepa-1c1c7 (Hepa-1) cells were treated with myristicin to assess the role of myristicin in the process of Cyp1a-1 induction. Treatment of Hepa-1 cells with myristicin increased Cyp1a-1 transcription in a dose-dependent manner as shown by analysis of 7-ethoxyresorufin
Nutmeg Intoxication Associated with Consumption as a Stupefacient
Gunaydin M, et al.
Journal of academic emergency medicine case reports, 8(3), 449-449 (2017)
Enzyme inhibition by molluscicidal components of Myristica fragrans Houtt. in the nervous tissue of snail Lymnaea acuminata
Jaiswal P, et al.
Enzyme Research, 2010(1), 49-56 (2010)
Myristicin-induced neurotoxicity in human neuroblastoma SK-N-SH cells
Lee BK, et al.
Toxicology Letters, 157(1), 49-56 (2005)
Active Filters
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