M7694

莫匹罗星

≥92% (HPLC), powder

• 同義詞: 5,9-Anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-[2E,8[2S,3S(1S,2S)]]-L-talonon-2-enonic acid 8-carboxyoctyl ester, BRL 4910A, Pseudomonic acid
• 經驗公式（希爾表示法）: C₂₆H₄₄O₉
• CAS號碼: 12650-69-0
• 分子量：: 500.62
• MDL號碼: MFCD01711620
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24724542
• NACRES: NA.77

屬性

• 化驗: ≥92% (HPLC)
• 形狀: powder
• 光學活性: [α]/D -15.7 to -20°, c = 1 in methanol
• 顏色: white to tan
• 溶解度: DMSO: ≥10 mg/mL
• 抗生素活性譜: fungi
• 作用方式: enzyme | inhibits; protein synthesis | interferes
• 起源: GlaxoSmithKline
• 儲存溫度: room temp
• SMILES 字串: [H][C@@]1(CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC(O)=O)[C@H](O)[C@@H]1O)C[C@@H]2O[C@@]2([H])[C@@H](C)[C@H](C)O
• InChI: 1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1
• InChI 密鑰: MINDHVHHQZYEEK-HBBNESRFSA-N

描述

一般說明

Mupirocin is produced by Pseudomonas fluorescens. Mupirocin is used to treat impetigo and skin infections.[1]

應用

Mupirocin has been used:

• for kinetic assay[2]
• to assess its resistance by performing turbidity assay[3][4]
• to determine its antimicrobial susceptibility[5]

生化／生理作用

Antibiotic; inhibits isoleucyl-tRNA synthetase (IRS).

特點和優勢

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

準備報告

Mupirocin is poorly soluble in water (26 mg/L), but highly soluble in DMSO (≥10 mg/mL). If sterilization is required, it is advisable to use filter sterilization with a 0.22 µm PTFE, Polypropylene, or Nylon filter membrane.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)