跳轉至內容
Merck
全部照片(2)

重要文件

M7195

Sigma-Aldrich

Anti-MO25 (C-terminus) 兔抗

enhanced validation

~2 mg/mL, affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-CAB39, Anti-CGI-66, Anti-Calcium binding protein 39

登入查看組織和合約定價


About This Item

分類程式碼代碼:
12352203
NACRES:
NA.44

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen ~40 kDa

物種活性

human, mouse (predicted), rat (predicted)

包裝

antibody small pack of 25 μL

加強驗證

recombinant expression
Learn more about Antibody Enhanced Validation

濃度

~2 mg/mL

技術

western blot: 0.5-1 μg/mL using HEK-293T cells expressing human MO25 and PC12 cell lysates

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... CAB39(51719)
mouse ... Cab39(12283)
rat ... Cab39(301574)

一般說明

MO25 is a 40 kDa scaffolding protein that interacts with STRADα and LKB1 to regulate tumor suppression. MO25 also facilitates the activation and cytoplasmic localization of LKB1 . Anti-MO25 (C-terminus) antibody detects human MO25 (approx. 40 kDa). The product is also predicted to react with rat and mouse MO25. Staining of the MO25 band in immunoblotting is specifically inhibited by the immunizing peptide.

免疫原

synthetic peptide corresponding to amino acids 323-341 located near the C-terminus of human MO25. This sequence is identical in chicken, dog, and bovine MO25 and highly conserved in rat and mouse MO25 (2 amino acid substitutions).

應用

Anti-MO25 (C-terminus) antibody is suitable for use in western blot (0.5-1 μg/mL using HEK-293T cells expressing human MO25 and in PC12 cell lysates).

外觀

Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到適合的產品?  

試用我們的產品選擇工具.


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Elton Zeqiraj et al.
Science (New York, N.Y.), 326(5960), 1707-1711 (2009-11-07)
The LKB1 tumor suppressor is a protein kinase that controls the activity of adenosine monophosphate-activated protein kinase (AMPK). LKB1 activity is regulated by the pseudokinase STRADalpha and the scaffolding protein MO25alpha through an unknown, phosphorylation-independent, mechanism. We describe the structure
Jérôme Boudeau et al.
The EMBO journal, 22(19), 5102-5114 (2003-10-01)
Mutations in the LKB1 protein kinase result in the inherited Peutz Jeghers cancer syndrome. LKB1 has been implicated in regulating cell proliferation and polarity although little is known about how this enzyme is regulated. We recently showed that LKB1 is

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務